Treatments of Chronic Pains

WO2008051889may also be flexible and capable of being attached to
Pellets containing an analgesic uniformly dispersed in aa patient without interfering with the patient's daily
lipid carrier such as cholesterol mixed with fatty acidroutine. The phototherapy bandage may easily
esters, can be used to provide long term pain relief. 5conform to the curves of a patient and may come in
mg cholesterol-tryglyceride- buprenorphine pelletsa variety of exterior shapes and sizes.
released the majority of drug in 24-48 hours afterWO2008021404
implant and provide clinically significant plasma levelsA composition providing cobalamine, cobalamine
of analgesia in mice for 3-9 days. Blood levels ofsubtype or cobalamine analog as an effective agent
analgesia peak at day-1 and are substantiallyfor topical or transdermal administration to alleviate
complete by day-5 depending on the level ofpain associated with a generalized or focal peripheral
buprenorphine. These results demonstrate that postneuropathic condition, such as carpal tunnel syndrome.
surgical implants provide clinically significant levels ofPain relief compositions for use in complementary
analgesia in the 24-48 hour period following surgerytherapy are also provided.
and thus obviate the time consuming, expensive, andUS2007276457
high-risk need to inject mice post surgery. The pelletsAn infrared heating device and therapy for lower
are safe and easy to use. Placed in the surgicalback pain includes a belt fastenable around a user so
wound at the end of surgery, they provide 2-3 daysthat the belt is overlaying at least a portion of a
of analgesia and obviate the need for subsequentlumbar region of the user. An infrared emitting
handling of the animal for pain therapy. The implantselement is adjustably positionable between the belt
have no detectable effect on mouse behavior,and at a selected area of the user's lumbar region
hematology, or liver chemistry. The unexpectedwhere a user desires pain relief therapy. A portable
release kinetics of the 5 mg pellet provides an idealpower supply is attachable to the belt and electrically
implant for post surgical analgesia. These implantsconnectable to the infrared emitting element so that
solve a significant problem facing scientists who usethe user can receive infrared therapy at specific
rodents in research and abide by international ofselected areas of the lower back while moving,
animal welfare.standing, sitting, reclining or sleeping.
US2008058689US2007255187
A phototherapy bandage capable of providingA device for providing therapy to a user including
radiation to a localized area of a patient forvibration and temperature modulation. The device
accelerating would healing and pain relief,provides mobile temperature modulation capabilities,
photodynamic therapy, and for aesthetic applications.mobile vibration capabilities, or a combination of the
The phototherapy bandage may include a flexible lighttwo. The device provides advantages to a person or
source that is continuous across the bandage foranimal including the ability to utilize the device in a
providing a selected light, such as a visible light, ahands-free manner. The device may also provide,
near-infrared light, or other light, having substantiallyunder certain circumstances, pain relief or healing
similar intensity across the bandage. The bandagetherapy to a person or animal.